Paracetamol + Phenylephrine + Chlorpheniramine Suspension

Not every pediatric cold syrup is created equal. Fever, congestion, and allergy don’t just occur together—they fuel one another, extending misery. An ineffective formula might provide temporary relief but not treat ongoing congestion, inflammation, or erratic fever spikes.

That’s why Paracetamol + Phenylephrine + Chlorpheniramine maleate suspension is formulated for persistent symptom relief:

  • Paracetamol reduces fever without oscillation.
  • Phenylephrine decongests with no dryness or rebound phenomenon.
  • Chlorpheniramine decreases mucus and airway inflammation.

But effectiveness doesn’t stop at ingredients—it’s how well they synergise. Therawin Formulations, WHO-GMP & ISO-certified manufacturer, assures:

  • Accurate dosing—balanced decongestant effect with fever reduction for prolonged relief.
  • Palatability optimisation—mild taste profile to ensure pediatric acceptability.
  • Homogeneous suspension—uniform particle dispersion, avoiding sedimentation for precise dosing.

Looking for a Paracetamol + Phenylephrine + Chlorpheniramine maleate suspension manufacturer in India that prioritises pediatric safety, taste, and absorption? Therawin Formulations delivers WHO-GMP & ISO-certified formulations, supporting pharma PCD franchise and third-party pharma manufacturing with batch-to-batch consistency, stability, and therapeutic efficacy.

Paracetamol Phenylephrine Chlorpheniramine Anticold Syrup Manufacturer In India

Generic name 

Paracetamol 125 mg + Phenylephrine 5 mg + Chlorpheniramine maleate 2 mg 

Pack 

60 ml / 100 ml

Description

Developed for paediatrics, this three-way suspension attacks fever, nasal congestion, and allergy symptomology with a precisely calibrated formulation:

  • Paracetamol (125 mg) – Reduces fever by blocking prostaglandin formation in the brain and mitigates mild to moderate pain.
  • Phenylephrine (5 mg) – A selective α1-adrenergic receptor agonist which narrows the nasal blood vessels, decreasing congestion and enhancing air flow through obstructed sinuses.
  • Chlorpheniramine maleate (2 mg) – A first-generation antihistamine which blocks H1 receptors, inhibiting sneezing, rhinorrhea, and other allergic reactions.

Children’s fever and nasal congestion usually demand a multi-targeted solution. This combination formulation not only alleviates fever but also decongests the nose and helps in allergic conditions, providing holistic symptom relief with pediatric safety as the priority.

Paracetamol + Phenylephrine + Chlorpheniramine maleate suspension uses

This pediatric suspension is typically given every 4-6 hours or as directed by a doctor. Unlike tablets or capsules, it must be measured carefully using a dosing spoon or syringe—not a household spoon—to ensure accuracy.

Shake the bottle well prior to each use to distribute the ingredients evenly. It is advisable to give the suspension after meals to reduce stomach upset. Always use a dosing spoon or syringe for precise measurement, as household spoons can result in improper dosing.

Recommended for:

  • Common cold & flu symptoms – Lowers fever, headache, body pains, and nasal congestion.
  • Sinus & nasal congestion – Relieves stuffy nose and breathing difficulty.
  • Allergic cold & rhinitis – Suppresses sneezing, watery eyes, and throat irritation.
  • Fever & body pain caused by viral infections – Provides quick relief and comfort.

Paracetamol + Phenylephrine + Chlorpheniramine maleate suspension side effects

Although well tolerated, some children might have mild side effects. Knowing how to deal with them can enhance comfort and compliance.

Common side effects & how to manage them

  • Drowsiness or light dizziness – Caused by antihistamine action and will usually pass. Encourage rest and avoid activities that need vigilance.
  • Nausea or mild stomach upset – Administer after meals to minimise stomach upset.
  • Dry mouth or throat irritation – Stimulate lots of fluids to avert dehydration.
  • Temporary rise in heart rate (through Phenylephrine) – Observe if it is apparent, but it will usually self-normalise.

When to seek medical attention

  • Severe allergic reactions – If rash, swelling, or difficulty breathing occurs, seek immediate medical help.
  • Persistent vomiting or refusal to eat – This may indicate an intolerance; consult a paediatrician.
  • Unusual drowsiness or weakness – May need dose adjustment.

Always follow dosage instructions carefully and avoid giving this with other cold or fever medications unless prescribed.

How to store Paracetamol + Phenylephrine + Chlorpheniramine maleate suspension?

  • Steer clear of temperatures above 30°C. Paracetamol degrades in heat, reducing its fever-reducing effect. Phenylephrine loses potency when exposed to prolonged warmth, making it less effective in relieving nasal congestion.
  • Avoid refrigeration or freezing. Cold temperatures cause precipitation, leading to uneven drug distribution—this means some doses might be too weak, while others too strong.
  • Keep the bottle tightly sealed after each use. Phenylephrine is sensitive to air exposure, which reduces its decongestant effect over time. An unsealed bottle allows moisture absorption, making Chlorpheniramine maleate clump, affecting uniform dosing.

Paracetamol + Phenylephrine + Chlorpheniramine maleate suspension manufacturer and supplier in India

Pediatric cold & fever suspension is a high-demand medication widely prescribed for seasonal flu, viral infections, and allergic colds—making them a must-have product for distributors and pharma retailers. However, low palatability, inconsistent formulations, and supply shortages remain common industry challenges.

That’s where Therawin Formulations make a difference.

With 35+ years of pharmaceutical excellence, we ensure:

  • WHO-GMP & ISO-certified production – Delivering consistent potency & safety.
  • Taste-masking technology – Improving child acceptance & compliance.
  • Custom branding & private labelling – Ideal for pharma PCD franchise distribution & third-party pharma manufacturing.
  • Reliable bulk stock availability – Ensuring uninterrupted supply.
  • Stringent quality control & regulatory compliance – Meeting industry safety standards.

For pharma PCD distributors, wholesalers, and third-party pharma manufacturers, Therawin Formulations offers high-quality, child-safe Paracetamol + Phenylephrine +  Chlorpheniramine maleate suspension—ensuring fast relief, high patient demand, and profitable distribution.

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