If a fungal infection runs out of control and becomes inflammation or secondary bacterial growth, a standard antifungal cream is not sufficient. Patients battling with recurring itching, swelling, redness, or cracked skin require an effective combination that acts fast.
That’s where Clobetasol + Neomycin + Miconazole cream comes in and provides targeted relief by killing fungi, preventing bacterial spread, and soothing inflammatory flare-ups all in one.
But efficacy isn’t merely ingredient-related—it’s about formulation accuracy. That’s why Therawin Formulations, a WHO-GMP & ISO-certified company, guarantees:
- Optimised steroid absorption—providing strength without undue skin thinning.
- Stable antibiotic action—providing consistent bacterial elimination without loss of potency.
- Advanced antifungal penetration—attacking deep-seated infections in hard-to-treat locations
Looking for a Clobetasol + Neomycin + Miconazole cream manufacturer in India? Therawin Formulations provides ready-for-market dermatology solutions with third-party pharma manufacturing and pharma PCD franchise offerings, ensuring quality, stability, and therapeutic integrity.

Generic name
Clobetasol + Neomycin + Miconazole
Pack
5 g / 10 g / 15 g
Description
This triple-action formulation provides comprehensive relief by addressing inflammation, bacterial infections, and fungal overgrowth simultaneously:
- Clobetasol Propionate – A potent corticosteroid that soothes inflammation, swelling, and itching in eczema, psoriasis, and dermatitis. Its rapid onset of action makes it one of the most potent topical steroids used for short periods.
- Neomycin Sulfate – A broad-spectrum antibiotic that inhibits bacterial growth at the origin and averts secondary infections in fissured, raw, or weeping skin. Critical in mixed infections, where bacteria coexist with fungal overgrowth.
- Miconazole Nitrate – A strong antifungal drug that kills fungal cell walls, attacking infections such as ringworm, athlete’s foot, and cutaneous candidiasis. Unlike other weaker antifungals, it penetrates deep skin layers for long-lasting action.
Inadequate healing usually follows incomplete treatment—usual antifungal cream is ineffective in controlling inflammation and secondary bacterial infections. This triple therapy addresses all three causes, facilitating quicker recovery and improving the skin barrier.
Clobetasol + Neomycin + Miconazole cream uses
A thin layer over the affected site twice a day, with clean, dry skin prior to use. Do not use for more than a limited time, particularly on sensitive spots such as the face, groin, or armpits, unless under medical supervision.
It is prescribed in cases where fungal infections become inflammatory, severe, or bacterial conditions.
Conditions treated:
- Fungal infections with inflammation – Ringworm, athlete’s foot, and jock itch with intense redness and itching.
- Mixed infections – Skin infections that are mixed fungal and bacterial overgrowth, requiring both antibiotic and antifungal therapy.
- Eczema & psoriasis with superinfection – When damaged skin is susceptible to bacterial or fungal colonisation.
- Intertrigo & candidiasis – Irritated, moist skin folds (groin, underarms) susceptible to fungal-bacterial co-infection.
- Seborrheic dermatitis – Ongoing inflammation of the scalp and face skin with associated fungal presence.
Clobetasol + Neomycin + Miconazole cream side effects
Common side effects & how to minimise them
- Burning, irritation, or redness – This also tends to happen with the overuse of corticosteroids. Apply only as instructed, and do not use on broken skin.
- Thinning of the skin (atrophy) – A hazard with long-term steroid use. Limit the duration of application and avoid occlusive dressing unless ordered.
- Fungal resistance – Discontinuation is improper or premature and causes recurrence. Complete the entire course as instructed by a healthcare provider.
- Localised hair growth – Fine hair growth occurs in treated areas in some patients, which is a reversible condition upon discontinuation.
When to seek immediate medical attention
- Severe allergic reactions – If there is rash, swelling, or breathing difficulty, discontinue the medicine and seek immediate medical attention.
- Blistering or skin discolouration – This may indicate adverse steroid effects requiring medical review.
- Worsening symptoms after 7 days – If infection persists or worsens, reassess with a dermatologist—an alternative treatment may be necessary.
How to store Clobetasol + Neomycin + Miconazole cream?
- Miconazole’s antifungal action weakens in high temperatures, making it less effective against fungal overgrowth. Hence it is important to store cream at room temperature (below 30°C).
- Store in a tight tube to avoid contamination. Contact with air can lead to cream separation, which interferes with absorption and application.
- Refrigerate or freeze—stability can be lost. Freezing leads to crystallisation, resulting in a grainy texture and difficulty spreading evenly across the skin.
Clobetasol + Neomycin + Miconazole cream manufacturer and supplier in India
Sustaining the stability and effectiveness of a steroid-antibiotic-antifungal blend is a major challenge in pharmaceutical production. Inconsistencies in the formulation lead to:
- Constrained potency between batches
- Shorter shelf life due to instability
- Poor patient compliance due to less consistent cream texture
At Therawin Formulations, we overcome these challenges by employing:
- API formulation is driven by precision for sustained release and maximum absorption.
- Batch-to-batch reproducibility, retaining potency, texture, and therapeutic stability.
- WHO-GMP-certified manufacturing, following very strict regulatory compliance.
- Comprehensive third-party pharma manufacturing and pharma PCD franchise support, enabling seamless branding and market entry.
Distributors and franchise partners need high-demand dermatological products backed by consistent quality and regulatory compliance. Our advanced formulation techniques ensure that every batch meets market demands for safety, stability, and effectiveness.
Partner with Therawin Formulations for regulatory-compliant, clinically reliable, and commercially viable dermatological formulations.